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Get Harder Erections

Erectile dysfunction

Also called ED, Can't get hard, Weak erections, Losing your erection

3 min plan70 min with every studyUpdated Sep 27, 2026

Who it's forA man who cannot get or keep an erection with his partner, or who loses it partway.

Tonight

  1. Take the five-question erection score
  2. Book the heart check and a morning testosterone test
  3. List every medicine and supplement you take
  4. Notice your morning erections this week

The plan

Arousalnitric oxideThe alarmAdrenalineThe switchPDE5The pipesthe arteries open
Figure 1. An erection is blood flow. Arousal releases nitric oxide, the artery wall relaxes and the vessel opens. Adrenaline cuts the signal, PDE5 switches it off, and the lining is where the heart numbers do their damage.

23 moves, in order, after 7 checks. Tap any row to see how.

Check first

Your erection scoreScore your erections before you change anythingCheck

The number to measure first: your IIEF-5 score

For: Everyone, first

Five questions that score your erections from 5 to 25. It is the number you start from and come back to.

How to check

  1. Answer the five questions about recent months.
  2. Add them up: 5 to 25.
  3. Write it down. 21 or less is the zone this page is for.
  4. Retake it once a month.
What it is
Five questions
When
Before you start
How often
Once a month

Standard practice

The US urology guideline recommends a standard questionnaire to measure severity and track treatment. On the five-question score: 22 to 25 is no problem, 17 to 21 mild, 12 to 16 mild to moderate, 8 to 11 moderate, 5 to 7 severe.

Reading the number

The starting number

In 1,152 men, a score of 21 or less picked out erection problems best.

¹ International journal of impotence research, 1999. The study is under The science, below.

Watch out

You need recent sex with a partner to answer it.

The science
In detail
Answer the five IIEF-5 questions about recent months, each scored 1 to 5. Write the total at the top of your log, and retake it once a month.
Found
21 or less means erection trouble. In 1,152 men, the five-question score was an excellent test for erection problems. A score of 21 or less picked them out best, and it sorts them into five levels, from none (22 to 25) to severe (5 to 7).
Why
A bad night is a feeling. A score is a place on a scale. The same five questions, answered again, show whether the plan is working.
Watch
The score needs a partner and some sex to answer. With no sex in the last months, it cannot be scored: note that instead.
How it is done
Five questions; Before you start; Once a month

The study

a cutoff score of 21 (range of scores, 5-25) discriminated best (sensitivity=0.98, specificity=0. 88).

PMID 10637462 · Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. · International journal of impotence research, 1999

The sentence around it

…Based on equal misclassification rates of ED and no ED, a cutoff score of 21 (range of scores, 5-25) discriminated best (sensitivity=0.98, specificity=0. 88).

ED was classified into five severity levels, ranging from none (22-25) through severe (5-7).

The heart checkBlood pressure, cholesterol and blood sugar, before anything elseCheck

The heart check: blood pressure, cholesterol, blood sugar

For: Everyone

Weak erections are often the first sign your blood vessels are in trouble. Get your heart numbers checked.

How to check

  1. Book a doctor's check.
  2. Ask for blood pressure, cholesterol, blood sugar or HbA1c, and kidney function.
  3. Ask for your 10-year heart risk score.
  4. Write the numbers down.
  5. Chest pain on effort? Tell the doctor before any sex pill.
What it is
One set of tests
When
Before the first pill
How often
Yearly

Standard practice

The specialist guideline: tell every man with erection problems that it is a risk marker for heart disease. Tests it lists: kidney function, fasting lipids, fasting glucose or HbA1c, and morning testosterone. Heart risk scores now count erection problems as a risk factor. The heart numbers are the same ones Live longer tracks.

Reading the number

Heart risk up 48%

Across 12 studies with 36,744 men, erection problems raised the risk of heart disease by 48%, even after the usual risks.

¹ Journal of the American College of Cardiology, 2011. The study is under The science, below.

Watch out

Chest pain on effort: see a doctor first. Sudden chest pain that stays: 911.

The science
In detail
Book a doctor's check: blood pressure, a fasting lipid panel, fasting glucose or HbA1c, kidney function, and a 10-year heart risk score. Erection trouble is often the first sign the blood vessels are struggling, years before the heart shows it.
Found
Heart disease risk up 48%. Twelve long-term studies, 36,744 men: erection problems raised the risk of heart disease by 48% and of stroke by 35%, beyond the usual risk factors. In a community study, erection problems predicted later heart trouble most strongly in the youngest men.
Why
The arteries in the penis are narrower than the ones in the heart. The same damage to the vessel lining shows up there first, so a failing erection is an early warning for the heart.
Watch
Chest pain or breathlessness on effort, with the erection trouble: see a doctor before any sex drug. Sudden chest pain that does not go away: 911.
How it is done
Blood pressure, lipids, glucose or HbA1c; Before the first pill; Then yearly, or as your doctor sets

The studies

The overall combined relative risks for men with ED compared with the reference group were 1.48 (95% confidence interval [CI]: 1.25 to 1.74) for CVD

PMID 21920268 · Erectile dysfunction and risk of cardiovascular disease: meta-analysis of prospective cohort studies. · Journal of the American College of Cardiology, 2011

The sentence around it

The overall combined relative risks for men with ED compared with the reference group were 1.48 (95% confidence interval [CI]: 1.25 to 1.74) for CVD, 1.46 (95% CI: 1.31 to 1.63) for coronary heart disease, 1.35 (95% CI: 1.19 to 1.54) for stroke, and 1.19 (95% CI: 1.05 to 1.34) for all-cause mortality.…

Young men with ED may be ideal candidates for cardiovascular risk factor screening and medical intervention.

PMID 19181643 · A population-based, longitudinal study of erectile dysfunction and future coronary artery disease. · Mayo Clinic proceedings, 2009

The physical examLet the doctor examine you: pulse, waist, penis, testiclesCheck

The physical exam

For: Everyone

A quick exam finds causes a questionnaire misses: a bend or lump, small testicles, a big waist.

How to check

  1. At the appointment, let the doctor examine you.
  2. Expect pulse, blood pressure and waist.
  3. Expect a check of the penis and testicles.
What it is
One exam
When
First appointment
How often
Once

Standard practice

The US urology guideline says every man with erection problems gets a history, a physical exam and selected lab tests. The exam covers pulse and blood pressure, the waist, signs of low testosterone, the penis for bends or plaques, and the testicles.

Reading the number

Part of every work-up

The specialist guideline makes a physical exam part of every check for erection problems.

¹ The journal of sexual medicine, 2018. The study is under The science, below.

Watch out

A new bend, a lump or painful erections: see your doctor.

The science
In detail
At the appointment the doctor takes your pulse, blood pressure and waist. They examine the penis for a bend or a lump, and the testicles for size.
Found
Two expert reviews of how to assess erection problems: every work-up includes a physical exam, alongside the history and standard blood tests for diabetes, cholesterol and low testosterone.
Why
The exam finds causes a questionnaire cannot. A scar or plaque can bend the penis. Small testicles or thin body hair point to low testosterone, and a big waist to the blood vessels.
Watch
A new bend, a hard lump or painful erections: see your doctor. It may be Peyronie’s disease, which has its own treatments.
How it is done
One exam; At the first appointment; Once

The studies

Patient evaluation for ED should encompass a variety of aspects, including medical history, sexual history, physical examination, psychological evaluation, laboratory testing, and possibly adjunctive testing.

PMID 30057280 · The 2018 Revision to the Process of Care Model for Evaluation of Erectile Dysfunction. · The journal of sexual medicine, 2018

The sentence around it

…Clinical implications Patient evaluation for ED should encompass a variety of aspects, including medical history, sexual history, physical examination, psychological evaluation, laboratory testing, and possibly adjunctive testing.

New management guidelines emphasize the need for a brief sexual and medical history, physical examination, and standard laboratory tests to rule out diabetes, dyslipidemia, or hypogonadism.

PMID 15146087 · Evaluation of the patient with erectile dysfunction: history, questionnaires, and physical examination. · Endocrine, 2004

Morning testosteroneA morning testosterone test, every man with erection troubleCheck

Morning testosterone

For: Everyone

A morning blood test for testosterone. If it is low, fixing it can help your erections.

How to check

  1. Ask for a total testosterone test.
  2. Have the blood taken in the morning.
  3. Low? Read Natural T, then talk to the doctor.
What it is
One blood test
When
Morning
How often
Once

Standard practice

The specialist guideline recommends measuring morning total testosterone in every man with erection problems. If it is low, a pill may work better with testosterone treatment added.

Reading the number

Low T: treatment helps

In 17 trials, where testosterone was low, treatment improved mild erection problems by an amount men notice.

¹ The lancet. Healthy longevity, 2023. The study is under The science, below.

Watch out

A normal result is common. Testosterone treatment stops sperm production: doctor only.

The science
In detail
Ask for a total testosterone blood test, taken in the morning. If it is low, Natural T is the page for raising it yourself, and Perfect TRT covers treatment through a doctor.
Found
Low level: treatment helps mild problems. With a true hormone deficiency, testosterone treatment is known to improve sexual function. Pooled data from 17 trials: where testosterone was low, treatment raised the full sexual function score by 5.52 points.
Why
Testosterone drives desire and helps keep the erection machinery working. When it is low, a pill works less well, and fixing the level can help both.
Watch
A normal result is common with erection trouble. Testosterone treatment stops sperm production: never start it without a doctor.
How it is done
One morning blood test; Morning; Once; repeat if low

The study

Testosterone replacement therapy is known to improve sexual function in men younger than 40 years with pathological hypogonadism.

PMID 37804846 · Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis. · The lancet. Healthy longevity, 2023

The sentence around it

…Background Testosterone replacement therapy is known to improve sexual function in men younger than 40 years with pathological hypogonadism.

Compared with placebo, testosterone treatment increased 15-item International Index of Erectile Function (IIEF-15) total score (mean difference 5·52 [95% CI 3·95-7·10]

The sentence around it

Compared with placebo, testosterone treatment increased 15-item International Index of Erectile Function (IIEF-15) total score (mean difference 5·52 [95% CI 3·95-7·10]; τ 2 =1·17; n=1412) and IIEF-15 erectile function subscore (2·14 [1·40-2·89]; τ 2 =0·64; n=1436), reaching the minimal clinically important difference for mild erectile dysfunction.…

Check what you takeList every medicine: SSRIs, finasteride, steroids firstCheck

Rule out: medicines and steroids

For: Anyone on a medicine

Some medicines and steroids cause erection problems. List what you take, and ask the doctor about a switch.

How to check

  1. Write down every medicine, supplement and substance.
  2. Flag antidepressants, finasteride, blood-pressure drugs and steroids.
  3. Ask the doctor about a switch. Never stop one yourself.
What it is
One list
When
Before the appointment
How often
At every new prescription

Standard practice

SSRI labels warn they may cause erectile dysfunction, and prescribers should ask about sexual function. The finasteride label lists erectile dysfunction, and sexual problems that continued after stopping. Anabolic steroids can cause erectile dysfunction. A doctor may switch a medicine that is causing it.

Reading the number

A cause you can change

In a large survey, erection problems tracked with heart disease, diabetes and the medicines for them.

¹ The Journal of urology, 1994. The study is under The science, below.

Watch out

Never stop a prescribed medicine suddenly. Ask the doctor first.

The science
In detail
List every medicine and substance. The usual ones: SSRI antidepressants, finasteride for hair, some blood-pressure drugs, and anabolic steroids. Never stop a prescribed medicine yourself: ask the doctor about a switch.
Found
Medicines are a listed cause. In a large community survey, erection problems tracked with heart disease, high blood pressure, diabetes, the medicines for them, and with anger and depression. The combined rate was 52%.
Why
Some drugs work against the erection directly. Antidepressants raise serotonin, which damps arousal; finasteride lowers a potent androgen; steroids shut down your own testosterone.
Watch
Stopping an antidepressant suddenly can bring withdrawal and relapse. Finasteride: the label lists sexual problems that continued after stopping. See Hair loss for the options.
How it is done
A list of everything you take; Before the first appointment; Once, and at every new prescription

The study

a higher probability of impotence was directly correlated with heart disease, hypertension, diabetes, associated medications, and indexes of anger and depression

PMID 8254833 · Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. · The Journal of urology, 1994

The sentence around it

…After adjustment for age, a higher probability of impotence was directly correlated with heart disease, hypertension, diabetes, associated medications, and indexes of anger and depression, and inversely correlated with serum dehydroepiandrosterone, high density lipoprotein cholesterol and an index of dominant personality.…

The combined prevalence of minimal, moderate and complete impotence was 52%.

Mood and sleepLow mood or loud snoring: your doctor firstCheck

Rule out: low mood and sleep apnea

For: Low mood, bad sleep

Low mood and sleep apnea both cause erection problems. Treat them and erections often come back.

How to check

  1. Low or flat most days for two weeks? See your doctor.
  2. Snoring, gasping, waking exhausted? See your doctor.
What it is
Two questions
When
Before you start
How often
At every review

Standard practice

Sleep apnea: breathing that stops and starts, gasping or choking noises, loud snoring and daytime exhaustion. See your doctor if you have the main symptoms. For low mood, Low mood is the page; for sleep, Deeper sleep.

Reading the number

Depression raises the odds

Across 49 studies, depression raised the odds of erection problems by 39%. Treating sleep apnea improved erections.

¹ The journal of sexual medicine, 2018. The study is under The science, below.

The science
In detail
Ask yourself two things. Has your mood been low, or have you lost interest in things, most days for two weeks? Do you snore, gasp in your sleep, or wake exhausted? Either one goes to your doctor.
Found
Depression: odds up 39%. Forty-nine studies: depression raised the odds of erection problems by 39%, and erection problems nearly tripled the odds of depression. Seven studies, 206 men: treating sleep apnea with a breathing machine at night raised the erection score.
Why
Depression flattens desire and arousal. Sleep apnea starves the body of oxygen at night and drags testosterone down. Treat the cause and the erection often follows.
How it is done
Two questions; Before you start; Again at every review

The studies

Patients reporting ED should be routinely screened for depression, whereas patients presenting with symptoms of depression should be routinely assessed for ED.

PMID 29960891 · Erectile Dysfunction and Depression: A Systematic Review and Meta-Analysis. · The journal of sexual medicine, 2018

The sentence around it

…Clinical implications Patients reporting ED should be routinely screened for depression, whereas patients presenting with symptoms of depression should be routinely assessed for ED.

The results suggest that continuous positive airway pressure therapy relive erectile dysfunction symptoms in patients with obstructive sleep apnoea.

PMID 32975905 · Continuous positive airway pressure therapy in obstructive sleep apnoea patients with erectile dysfunction-A meta-analysis. · The clinical respiratory journal, 2021

The sentence around it

…Conclusion The results suggest that continuous positive airway pressure therapy relive erectile dysfunction symptoms in patients with obstructive sleep apnoea.

Porn and the patternWorks alone but not with a partner: points to nerves; the heart check still standsCheck

Rule out: the pattern, and feeling hooked

For: Everyone

Notice when it works. Fine alone or in the morning, but not with your partner? That points to nerves. The heart check still stands.

How to check

  1. Notice morning erections this week.
  2. Notice whether it works alone.
  3. Works alone, not with a partner: that points to nerves. Take the head route below, and keep the heart check.
  4. Feel hooked on porn? Say so to the doctor.
What it is
A week
When
This week
How often
Once

Standard practice

Specialists ask whether it happens only with a partner, and about morning and solo erections. Morning or night erections suggest a psychological part that needs a closer look.

Reading the number

Feeling hooked predicted it

In a survey of 942 men, feeling addicted to porn predicted more erection problems.

¹ The journal of sexual medicine, 2021. The study is under The science, below.

The science
In detail
Notice when the erection works. Fine in the morning, or alone with porn, but not with your partner, points to nerves and the head. Gone everywhere points to the body. Either way, the heart check stays. Ask too whether you feel hooked on porn.
Found
Feeling hooked predicted ED. In a survey of 942 men, feeling addicted to porn predicted more erection problems. The researchers advise doctors to treat that feeling as a possible cause.
Why
If the hardware works at night or alone, the blood supply is there. What blocks it with a partner is the alarm system: pressure, worry and watching yourself.
How it is done
A week of noticing; Morning, alone, with a partner; Once, then at reviews

The study

self-perceived IP addiction uniquely predicted increased ED, EE and individual sexual dissatisfaction.

PMID 34400111 · Pornography Addiction: An Exploration of the Association Between Use, Perceived Addiction, Erectile Dysfunction, Premature (Early) Ejaculation, and Sexual Satisfaction in Males Aged 18-44 Years. · The journal of sexual medicine, 2021

The sentence around it

…Further, self-perceived IP addiction uniquely predicted increased ED, EE and individual sexual dissatisfaction.

We recommend that clinicians consider self-perceived IP addiction as a possible contributing factor to sexual dysfunction.

Free habits

1Aerobic training40 minutes of hard cardio, four times a weekStrong evidence

Get fit: hard cardio, four times a week

For: Everyone

Hard cardio opens up the arteries that feed an erection. Forty minutes, four times a week.

What to do

  1. Pick a cardio you can push: run, bike, row.
  2. Go 40 minutes, hard enough that talking is work.
  3. Four times a week, for six months.
How much
40 minutes
When
4 times a week
How long
6 months

What happened in the studies

Erection score up 3.85

In 7 trials with 478 men, exercise raised the erection score by 3.85 points, most of all hard cardio.

¹ British journal of sports medicine, 2017. The study is under The science, below.

Watch out

Chest pain or breathlessness on effort: see a doctor first.

The science
In detail
Forty minutes of moderate to hard cardio, four times a week: running, cycling, rowing, a hard incline walk. Hard enough that talking is work. Keep it up for six months.
Found
Erection score up 3.85 points. Seven trials, 478 men: exercise raised the erection score by about 3.9 points, most of all moderate to vigorous aerobic work. A review set the dose at 40 minutes, four times a week, 160 minutes a week for six months.
Why
Hard cardio makes the vessel lining release more nitric oxide, the gas that opens the arteries to the penis. It lowers blood pressure and blood sugar, the things that damage those arteries.
Watch
Chest pain or breathlessness on effort: see a doctor before you train hard. Build up over weeks.

The studies

Pooled data showed a statistically significant improvement in erectile function score (mean difference 3.85, 95% CI 2.33 to 5.37).

PMID 27707739 · Physical activity and exercise for erectile dysfunction: systematic review and meta-analysis. · British journal of sports medicine, 2017

Recommendations of PA to decrease ED should include supervised training consisting of 40 minutes of aerobic exercise of moderate to vigorous intensity 4 times per week.

PMID 29661646 · Physical Activity to Improve Erectile Function: A Systematic Review of Intervention Studies. · Sexual medicine, 2018

The sentence around it

…Conclusion Recommendations of PA to decrease ED should include supervised training consisting of 40 minutes of aerobic exercise of moderate to vigorous intensity 4 times per week.

2Lose the bellyCarry extra weight? Lose 10% of itModerate evidence

Lose weight, if you carry extra

For: Carrying extra weight

Losing belly fat lifts testosterone and calms inflammation. Both help erections.

What to do

  1. Aim to lose 10% of your body weight.
  2. Eat less and move more.
  3. Weigh yourself weekly and watch the trend.
How much
Lose 10%
When
Weekly weigh-in
How long
Months

What happened in the studies

17against 3 back to normal

In a 2-year trial with 110 men, 17 on the weight-loss plan reached a normal erection score, against 3 on general advice.

¹ JAMA, 2004. The study is under The science, below.

The science
In detail
If your waist is big, aim to lose at least 10% of your body weight, eating less and moving more. Weigh yourself weekly and track the trend.
Found
17 back to normal, against 3. A two-year trial, 110 men: advice to lose 10% of body weight and move more raised the erection score from 13.9 to 17. Seventeen men on the plan reached a normal score, against 3 on general advice.
Why
Belly fat drives inflammation and lowers testosterone. Both damage the vessel lining. Losing it brought the inflammation markers down in the trial, along with the erection gains.

The study

Seventeen men in the intervention group and 3 in the control group (P =.001) reported an IIEF score of 22 or higher.

PMID 15213209 · Effect of lifestyle changes on erectile dysfunction in obese men: a randomized controlled trial. · JAMA, 2004

The mean (SD) IIEF score improved in the intervention group (from 13.9 [4.0] to 17 [5]; P<.001)

3Quit smokingStop smoking; rescore at six monthsModerate evidence

Stop smoking and vaping nicotine

For: Smokers

Smoking damages the arteries that feed an erection. Quit, and erections get firmer.

What to do

  1. Set a quit date.
  2. Use a stop-smoking service or nicotine patches.
  3. Rescore your erections at 6 months.
How much
Stop
When
Now
How long
Rescore at 6 months

What happened in the studies

Firmer after quitting

Six months after quitting, erection scores rose at every age tested.

¹ BJU international, 2012. The study is under The science, below.

The science
In detail
Stop smoking. Use a stop-smoking service and nicotine replacement if you need it: a patch while you quit is fine. Score your erections again six months after you stop.
Found
Scores up 6 months after quitting. In an 8-week quit program with nicotine patches, men who stayed off cigarettes had firmer erections a month later. In another study, erection scores rose six months after quitting, at every age tested.
Why
Smoke damages the vessel lining and narrows the arteries to the penis. Stopping lets the lining recover.

The studies

Smoking cessation significantly enhances both physiological and self-reported indices of sexual health in long-term male smokers, irrespective of baseline erectile impairment.

PMID 21883852 · Association between smoking cessation and sexual health in men. · BJU international, 2012

The sentence around it

…Conclusions Smoking cessation significantly enhances both physiological and self-reported indices of sexual health in long-term male smokers, irrespective of baseline erectile impairment.

quitting smoking improves male sexual function in all age groups between 30-60 years of age regardless of pack-year and education level.

PMID 32374127 · Effect of smoking cessation on sexual functions in men aged 30 to 60 years. · International braz j urol, 2020

The sentence around it

…Conclusions Erectile function is directly proportional to the degree of exposure to smoking, and quitting smoking improves male sexual function in all age groups between 30-60 years of age regardless of pack-year and education level.

4Mediterranean eatingVegetables, beans, nuts, fish and olive oilModerate evidence

Eat Mediterranean

For: Everyone

Vegetables, beans, nuts, fish and olive oil. This way of eating helps your blood vessels and your erections.

What to do

  1. Cook with olive oil.
  2. Fill the plate with vegetables, beans and whole grains.
  3. Fish and nuts most weeks; less red and processed meat.
How much
Most meals
When
Daily
How long
For good

What happened in the studies

13against 2 back to normal

In a 2-year study of 65 men, 13 on the diet reached a normal erection score, against 2 on the control diet.

¹ International journal of impotence research, 2006. The study is under The science, below.

The science
In detail
Build meals from vegetables, fruit, whole grains, beans, nuts and fish, cooked in olive oil. Keep red and processed meat and white bread low.
Found
13 back to normal, against 2. Two years on a Mediterranean diet, 65 men: 13 on the diet reached a normal erection score, against 2 on the control diet. A review found it beat control diets for erection problems.
Why
This way of eating improves the lining of the blood vessels and lowers inflammation. Both improved in the trial.

The studies

There were 13 men in the intervention group and two in the control group (P=0.015) that reported an IIEF score of 22 or higher.

PMID 16395320 · Mediterranean diet improves erectile function in subjects with the metabolic syndrome. · International journal of impotence research, 2006

In clinical trials, Mediterranean diet was more effective than a control diet in ameliorating ED or restoring absent ED in people with obesity or metabolic syndrome.

PMID 20487239 · Dietary factors, Mediterranean diet and erectile dysfunction. · The journal of sexual medicine, 2010

5Fix the risk factorsTreat blood pressure, cholesterol and sugar; drink under 8 US standard drinks (14 UK units)Strong evidence

Treat the heart numbers, cut the drink

For: Everyone

Bring down blood pressure, cholesterol and sugar, and drink less. Erections improve with them.

What to do

  1. Treat what the heart check finds.
  2. Keep alcohol under 8 US standard drinks (14 UK units) a week.
  3. Ride over 3 hours a week? Ease off for a while.
How much
What the check finds
When
Daily
How long
Rescore at 3 months

Standard practice

Healthy changes that can help: lose weight, stop smoking, eat well, exercise daily and reduce stress. Drink no more than 8 US standard drinks (14 UK units) a week. Ride over 3 hours a week? Ease off for a while. Lower ApoB and blood sugar each have their own page: Lower ApoB, Blood sugar.

What happened in the studies

Erection score up 2.66

In 6 trials with 740 men, lifestyle change and heart-risk treatment raised the erection score by 2.66 points.

¹ Archives of internal medicine, 2011. The study is under The science, below.

The science
In detail
Whatever the heart check finds, treat it: blood pressure, cholesterol, blood sugar. Keep alcohol under 8 US standard drinks (14 UK units) a week. If you ride more than 3 hours a week, ease off for a while.
Found
Six trials, 740 men: lifestyle change and drugs for heart risk factors raised the erection score by 2.66 points. The four lifestyle trials alone, 597 men: 2.40 points.
Why
High blood pressure, high cholesterol and high sugar all wear down the vessel lining. Bring them down and the erection has better blood flow to work with.

The study

Lifestyle modifications and pharmacotherapy for CV risk factors were associated with statistically significant improvement in sexual function (IIEF-5 score): weighted mean difference, 2.66 (95% CI, 1.86-3.47).

PMID 21911624 · The effect of lifestyle modification and cardiovascular risk factor reduction on erectile dysfunction: a systematic review and meta-analysis. · Archives of internal medicine, 2011

lifestyle modification and pharmacotherapy for CV risk factors are effective in improving sexual function in men with ED.

The sentence around it

…Conclusion The results of our study further strengthen the evidence that lifestyle modification and pharmacotherapy for CV risk factors are effective in improving sexual function in men with ED.

6Train the pelvic floorPelvic floor squeezes, three times a day, for three monthsModerate evidence

Train the pelvic floor

For: Everyone

The muscles at the base of the penis hold the blood in. Train them and erections get firmer.

What to do

  1. Find the muscle that stops your pee.
  2. Squeeze, hold, release. Build to 3 sets a day.
  3. Give it 3 months. A physical therapist can check your technique.
How much
3 sets
When
3 times a day
How long
3 months

What happened in the studies

Score up 6.74 points

In a trial with 55 men, 3 months of pelvic floor training raised the erection score by 6.74 points.

¹ The British journal of general practice, 2004. The study is under The science, below.

Watch out

Pelvic pain or a tight pelvic floor: see a physical therapist first. Relax it before you train it.

The science
In detail
Squeeze the muscle that stops the flow of pee and holds in gas. Hold, release, and build to three sets a day. A pelvic health physical therapist with biofeedback teaches it right. Give it three months.
Found
Erection score up 6.74 points. A trial of 55 men: three months of pelvic floor exercise with biofeedback raised the erection score by 6.74 points against lifestyle advice. Ten trials: every one showed improvement.
Why
The pelvic floor muscles squeeze the base of the penis and slow the blood leaving it. Stronger muscles hold the erection harder and longer.
Watch
If the pelvic floor is already tight, more squeezing makes it worse. Pelvic pain, a weak stream or pain on ejaculation: see a physical therapist, and learn to let go first.

The studies

At 3 months, compared with controls, men in the intervention group showed significant mean increases in the erectile function domain of the IIEF (6.74 points, P = 0.004)

PMID 15527607 · Randomised controlled trial of pelvic floor muscle exercises and manometric biofeedback for erectile dysfunction. · The British journal of general practice, 2004

The sentence around it

…Results At 3 months, compared with controls, men in the intervention group showed significant mean increases in the erectile function domain of the IIEF (6.74 points, P = 0.004); anal pressure (44.16 cmH(2)O, P <0.001); and digital anal grades (1.5 grades, P <0.001).…

Among the measures of ED, all trials showed comparative improvement and cure rates in response to treatment.

PMID 30979506 · Pelvic floor muscle training improves erectile dysfunction and premature ejaculation: a systematic review. · Physiotherapy, 2019

The deep dive on this

Next steps

7Sensate focus at homeNerves with a partner: sensate focus at home, as a coupleEarly evidence

The home program: sensate focus, as a couple

For: Nerves with a partner

Touch with your partner, with no goal of sex, takes the pressure off. Done at home, step by step.

What to do

  1. Agree with your partner: no sex for now, just touch.
  2. Take turns touching everywhere except the genitals. Notice the feeling, not the erection.
  3. After a few sessions, add genital touch, still with no goal.
  4. Then move toward sex slowly. If the pressure comes back, step back a stage.
  5. Or follow a structured online self-help program for about 7 weeks.
How much
A few sessions a week
When
At home
How long
About 7 weeks

What happened in the studies

Better at 6 months

In a 7-week online program, erection scores kept improving, with a large gain 6 months on.

¹ Sexual medicine reviews, 2026. The study is under The science, below.

Watch out

Nothing changes, or it fails alone and in the morning too: the heart check and your doctor first.

The science
In detail
If it works alone but fails with a partner, or fear of failing has become the problem, run a sensate focus program at home with your partner. Start with touch and no goal of sex, then build up step by step. A structured online self-help program does the same over about 7 weeks.
Found
Gain grew to d 0.88 at 6 months. A review of 21 studies: online programs improved erections and sexual satisfaction against control. In a 7-week online program, the gain on the erection score was small at the end and large 6 months later.
Why
Fear of losing the erection fires adrenaline, and adrenaline shuts the erection down. Watching yourself mid-sex feeds the loop. Touch with no goal takes the pressure off, so arousal can build again.
Watch
If nothing changes after the program, or erections fail alone and in the morning too, the cause is likely physical: the heart check and your doctor come first.

The studies

Overall, web-based ICBT and psychoeducational interventions improved erectile function and sexual satisfaction compared with control conditions.

PMID 41926207 · Internet-based cognitive behavioral therapy, web-based counseling, and online/digital psychoeducation for male sexual dysfunction: a systematic review. · Sexual medicine reviews, 2026

increased at the 6-month follow-up (d = 0.88).

PMID 21797983 · A randomized controlled trial of guided Internet-delivered cognitive behavioral therapy for erectile dysfunction. · The journal of sexual medicine, 2011

Early research

8Low-intensity shockwaveInvestigational: shockwave, as a trial or with a urologistEarly evidence

Shockwave therapy

For: Early research

Sound waves aimed at the penis, meant to grow new blood vessels. Early and still in trials.

What to do

  1. Talk to a urologist about a trial.
  2. Keep the lifestyle moves going.
  3. Rescore at the end of the course.
How much
A course
When
Over weeks
How long
Investigational

Standard practice

The main US guideline calls low-intensity shockwave investigational and keeps it to approved trials. The European guideline gives it a weak recommendation for mild erection problems of blood-vessel origin.

What happened in the studies

Score up, low certainty

Across 21 trials with 1,357 men, shockwave raised the erection score, on low-certainty evidence.

¹ BJU international, 2026. The study is under The science, below.

Watch out

Early evidence. How long it lasts is not settled.

The science
In detail
Still investigational: the main US guideline keeps it to trials. If you try it, do it as a trial or with a urologist, a course of sessions over weeks, on top of the moves above.
Found
Long-term score up 5.25, low certainty. Twenty-one trials against a fake treatment, 1,357 men: shockwave raised the erection score by about 3.9 points short term and about 5.3 long term. Side effects matched the fake treatment.
Why
Low-energy sound waves are thought to trigger new small blood vessels in the erectile tissue, so the aim is better flow, not a one-night fix.
Watch
Low-certainty evidence, and how long any gain lasts is not settled. It is not for erection problems from nerves after surgery.

The study

Low-intensity shockwave therapy may improve long-term erectile function and short-term rigidity

PMID 41906634 · Low-intensity shockwave therapy for erectile dysfunction: An abridged Cochrane review. · BJU international, 2026

The sentence around it

…Conclusions Low-intensity shockwave therapy may improve long-term erectile function and short-term rigidity, with little difference in discontinuation or adverse events.…

Long-term function may improve (MD 5.25, 95% CI 2.47-8.04; I 2 = 87%; five studies; low-certainty).

9Red Ginseng900 mg three times a day, early in the dayEarly evidence

Red ginseng

For: Early research

A root that may help erections. Early trials, pointing the right way.

What to do

  1. Take 900 mg three times a day.
  2. All doses before the afternoon.
  3. Give it 8 weeks.
How much
900 mg, 3 times
When
Early in the day
How long
8 weeks

Standard practice

European guideline: a weak yes. For mild problems, when drugs are turned down. Expect a mild gain.

What happened in the studies

2.4times the odds

In 6 trials with 349 men, red ginseng made improvement 2.4 times as likely as a dummy pill.

¹ British journal of clinical pharmacology, 2008. The study is under The science, below.

Watch out

Can keep you up. Take it early.

The science
In detail
900 mg three times a day, the trial dose, before the afternoon. Give it eight weeks.
Found
2.4 times as likely to improve. Six trials against a placebo, 349 men: red ginseng made improvement 2.4 times as likely as placebo. A later review: ginseng may improve men’s own sense they can have sex.
Why
The steamed root’s compounds raise nitric oxide in the vessel wall of the penis.
Watch
It can keep you awake: take it early. It may add to blood-pressure and blood-sugar drugs.
The doses the studies used900 mg, three times a day the trial dose, eight weeks
900 mg, three times a day

The ginseng dose was 900 mg. 3 times daily PMID 12394711

The studies

The meta-analysis of these data showed a significant effect (n = 349, risk ratio, 2.40; 95% CI of 1.65, 3.51

PMID 18754850 · Red ginseng for treating erectile dysfunction: a systematic review. · British journal of clinical pharmacology, 2008

The sentence around it

The meta-analysis of these data showed a significant effect (n = 349, risk ratio, 2.40; 95% CI of 1.65, 3.51, p < 0.00001, heterogeneity: tau(2) = 0.05, chi(2) = 6.42, p = 0.27, I(2) = 22%).…

Ginseng may improve men's self-reported ability to have intercourse.

PMID 33871063 · Ginseng for erectile dysfunction. · The Cochrane database of systematic reviews, 2021

The deep dive on this

10L-Arginine1.5 to 5 g a day, for mild to moderate problemsEarly evidence

Arginine

For: Early research

An amino acid your body turns into the gas that opens blood vessels. It helped mild problems in trials.

What to do

  1. Take 1.5 to 5 grams a day.
  2. Give it 4 to 8 weeks.
How much
1.5 to 5 grams
When
Daily
How long
4 to 8 weeks

Standard practice

European guideline: a weak yes. For mild problems, when drugs are turned down. Expect a mild gain.

What happened in the studies

3.37times the odds

In 10 trials with 540 men, 1.5 to 5 grams a day improved erections, with 3.37 times the odds of a dummy pill.

¹ The journal of sexual medicine, 2019. The study is under The science, below.

Watch out

Stomach upset at high doses. It adds to blood-pressure pills.

The science
In detail
1.5 to 5 g a day, the range the trials used, for mild to moderate problems. Judge at 4 to 8 weeks.
Found
Odds 3.37 times placebo. Ten trials, 540 men: for mild to moderate problems, 1.5 to 5 g of arginine improved erections, with 3.37 times the odds of placebo. Side effects ran at 8.3%, none severe.
Why
Arginine is what the vessel wall turns into nitric oxide, the gas that opens the arteries to the penis. Much of a swallowed dose is lost in the gut, so the trials used grams.
Watch
Stomach upset at the top of the range. It adds to blood-pressure drugs.
The doses the studies used1.5 g the bottom of the pooled range
1.5 g5 g

dosage ranging from 1,500 to 5,000 mg PMID 30770070

The study

arginine supplements with dosage ranging from 1,500 to 5,000 mg significantly improved ED compared with placebo or no treatment (odds ratios, 3.37 [1.29, 8.77], P = .01

PMID 30770070 · The Potential Role of Arginine Supplements on Erectile Dysfunction: A Systemic Review and Meta-Analysis. · The journal of sexual medicine, 2019

The sentence around it

…The analysis demonstrated that arginine supplements with dosage ranging from 1,500 to 5,000 mg significantly improved ED compared with placebo or no treatment (odds ratios, 3.37 [1.29, 8.77], P = .01, I2 = 44).…

The adverse effect rate in the arginine-treated group was 8.3%, and that in the placebo group was 2.3%, none of which were severe.

The deep dive on this

11L-Citrulline1.5 g a day, for mild problemsEarly evidence

Citrulline

For: Early research

An amino acid your body turns into arginine. It helped mild problems in a small trial.

What to do

  1. Take 1.5 grams a day.
  2. Give it a month.
How much
1.5 grams
When
Daily
How long
A month

What happened in the studies

12of 24 reached full hardness

In a small trial, 12 of 24 men reached full hardness on citrulline, against 2 on a dummy pill.

¹ Urology, 2011. The study is under The science, below.

Watch out

Mild stomach upset. It adds to blood-pressure pills.

The science
In detail
1.5 g a day, the trial dose, for mild problems. Give it a month.
Found
12 of 24 reached full hardness, against 2. A month-long trial, 24 men, mild problems at the start: 12 reached full hardness on citrulline, against 2 on placebo. Every man who improved was very satisfied, and there were no side effects.
Why
Citrulline slips past the gut and liver and is turned into arginine in the kidneys. That raises the raw material for nitric oxide more than arginine itself does.
Watch
Mild stomach upset. It may add to blood-pressure drugs.
The doses the studies used1.5 g a day the trial dose, one month
1.5 g a day

L-citrulline, 1.5 g/d, for another month PMID 21195829

The study

The improvement in the erection hardness score from 3 (mild ED) to 4 (normal erectile function) occurred in 2 (8.3%) of the 24 men when taking placebo and 12 (50%) of the 24 men when taking L-citrulline (P < .01).

PMID 21195829 · Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction. · Urology, 2011

All patients reporting an erection hardness score improvement from 3 to 4 reported being very satisfied.

The deep dive on this

12PycnogenolArginine with pine bark extract, 2 to 3 monthsEarly evidence

French maritime pine bark, with arginine

For: Early research

Arginine with a pine bark extract. The pair raised erection scores in small trials.

What to do

  1. Take 1.7 grams of arginine a day.
  2. Add 40 mg of pine bark extract twice a day; three times a day from month three.
  3. Give the pair 2 to 3 months, then rescore.
How much
1.7 g + 80 to 120 mg
When
Daily
How long
2 to 3 months

Standard practice

European guideline: a weak yes for arginine supplements. For mild problems, when drugs are turned down. Expect a mild gain.

What happened in the studies

Erection scores up, 3 trials

In 3 trials with 184 men, pine bark with arginine raised erection scores. In one, 92.5% had normal erections by month three.

¹ Frontiers in endocrinology, 2023. The study is under The science, below.

Watch out

It thins the blood a little: ask a doctor first if you take aspirin or a blood thinner. It adds to blood-pressure and diabetes pills. With nitrates or an erection pill, ask first. Autoimmune condition or immune drugs: ask first. Stomach upset, dizziness or headache.

The science
In detail
Early research: 1.7 g of arginine a day, with French maritime pine bark extract, 40 mg twice a day, then three times a day. The trial gave arginine alone for a month, then added the bark. Give the pair 2 to 3 months.
Found
3 trials, 184 men. Three trials, 184 men: the bark with arginine raised erection, satisfaction, orgasm and desire scores against control. In a 3-month trial of 40 men, normal erections rose to 80% after the second month and 92.5% after the third.
Why
Arginine is the raw material for nitric oxide, the gas that opens the arteries to the penis. The bark switches on the enzyme in the vessel wall that makes it, so the two work as a pair.
Watch
The bark slows platelets from clumping and adds to aspirin: ask a doctor first if you take aspirin or a blood thinner. Both parts can lower blood pressure, and the bark can lower blood sugar, so they add to blood-pressure and diabetes drugs. With a nitrate or an erection pill, ask a doctor first. With an autoimmune condition or on immune-suppressing drugs, ask first. Stomach upset, dizziness and headache are the usual side effects.
The doses the studies used1.7 g arginine a day the trial dose, with the bark at 40 mg twice, then three times a day
1.7 g arginine a day

equivalent to 1.7 g L-arginine per day PMID 12851125

The studies

there were significant differences in the international index of erectile function scores (erectile domain), intercourse satisfaction scores, orgasmic function scores, overall satisfaction scores, and sexual desire scores between the combination treatment group and the control group.

PMID 37908749 · Efficacy of L-arginine and Pycnogenol ® in the treatment of male erectile dysfunction: a systematic review and meta-analysis. · Frontiers in endocrinology, 2023

The sentence around it

…The results of the current meta-analysis showed that there were significant differences in the international index of erectile function scores (erectile domain), intercourse satisfaction scores, orgasmic function scores, overall satisfaction scores, and sexual desire scores between the combination treatment group and the control group.

after the third month of treatment, 92.5% of the men experienced a normal erection.

PMID 12851125 · Treatment of erectile dysfunction with pycnogenol and L-arginine. · Journal of sex & marital therapy, 2003

The sentence around it

…Finally, after the third month of treatment, 92.5% of the men experienced a normal erection.

The deep dive on this

13Tribulus terrestrisTribulus, 1,500 mg a day, 12 weeksEarly evidence

Tribulus

For: Early research

A plant extract that raised erection scores against a dummy pill in eight trials.

What to do

  1. Take two 250 mg tablets, three times a day, after meals.
  2. Use a standardized extract with a third-party test.
  3. Give it 12 weeks, then rescore.
How much
1,500 mg a day
When
After meals
How long
12 weeks

What happened in the studies

Score up 3.23 points

Across 8 trials, tribulus raised the five-question erection score 3.23 points more than a dummy pill.

¹ International journal of impotence research, 2026. The study is under The science, below.

Watch out

Stomach upset. Rare liver or kidney trouble, or breast swelling: stop and see a doctor. Often faked: choose a third-party tested product. Prostate problem or regular medicines: ask first.

The science
In detail
Early research: a tribulus extract standardized to its saponins, two 250 mg tablets three times a day after meals, the trial dose. Give it 12 weeks.
Found
Erection score up 3.23 points. Eight trials pooled: tribulus beat placebo on both erection questionnaires, by 3.23 points on the five-question score. A 12-week trial, 180 men: the erection score rose 2.70 points more than on placebo, and side effects matched placebo.
Why
Its saponins are thought to work on the nitric oxide route that opens the arteries to the penis.
Watch
Stomach upset is the usual side effect. Rare reports of liver or kidney injury, and of breast swelling: stop and see a doctor if either shows. Products are often adulterated: choose one tested by a third party. With a prostate problem, ask a doctor first. On regular medicines, ask a pharmacist first.
The doses the studies used1,500 mg a day two 250 mg tablets, three times a day, 12 weeks
1,500 mg a day

3×2 film-coated tablets daily after meals PMID 28364864

The studies

on both the IIEF-5 [MD 3.23 (95%CI 1.89, 4.58), p < 0.00001] and IIEF-15 [MD 14.44 (95%CI 5.75, 23.14), p = 0.001], Tribulus terrestris outperformed placebo.

PMID 40360723 · Tribulus terrestris for management of patients with erectile dysfunction: a systematic review and meta-analysis of randomized trials. · International journal of impotence research, 2026

The sentence around it

…Additionally, on both the IIEF-5 [MD 3.23 (95%CI 1.89, 4.58), p < 0.00001] and IIEF-15 [MD 14.44 (95%CI 5.75, 23.14), p = 0.001], Tribulus terrestris outperformed placebo.

The difference between TT and placebo was 2.70 (95% CI 1.40, 4.01)

PMID 28364864 · Evaluation of the efficacy and safety of Tribulus terrestris in male sexual dysfunction-A prospective, randomized, double-blind, placebo-controlled clinical trial. · Maturitas, 2017

The sentence around it

The difference between TT and placebo was 2.70 (95% CI 1.40, 4.01) for the ITT population.…

The deep dive on this

14MacaMaca, 2,400 mg a day, 12 weeksEarly evidence

Maca root

For: Early research

A root that raised erection scores a little in a 12-week trial.

What to do

  1. Take 2,400 mg of maca extract a day, in the morning.
  2. Choose a product tested for heavy metals.
  3. Judge it at 12 weeks.
How much
2,400 mg
When
Morning
How long
12 weeks

What happened in the studies

Score up 1.6, against 0.5

In a 12-week trial, the erection score rose 1.6 points on maca, against 0.5 on a dummy pill.

¹ Andrologia, 2009. The study is under The science, below.

Watch out

Gut upset. Poorly sourced products can carry heavy metals. It can disturb sleep. Thyroid or hormone-sensitive condition: ask first.

The science
In detail
Early research: 2,400 mg of maca dry extract a day, the trial dose, for 12 weeks. Choose a product tested for heavy metals.
Found
A 12-week trial: the five-question erection score rose 1.6 points on maca, against 0.5 on placebo. Sexual and general wellbeing scores rose more on maca too.
Why
Maca seems to act through the brain rather than the sex hormones. The exact route is not yet known.
Watch
Gut discomfort. Poorly sourced products can carry heavy metals: choose one tested for them. It can overstimulate and disturb sleep for some: take it in the morning. It is a brassica, so with a thyroid condition, ask a doctor first. With a hormone-sensitive condition, such as prostate cancer, ask first.
The doses the studies used2,400 mg a day the trial dose, 12 weeks
2,400 mg a day

Maca dry extract, 2400 mg PMID 19260845

The study

patients taking Maca experienced a more significant increase than those taking placebo (1.6 +/- 1.1 versus 0.5 +/- 0.6, P < 0.001).

PMID 19260845 · Subjective effects of Lepidium meyenii (Maca) extract on well-being and sexual performances in patients with mild erectile dysfunction: a randomised, double-blind clinical trial. · Andrologia, 2009

the Maca group higher than that of placebo group (+9 +/- 6 versus +6 +/- 5, P < 0.05).

The deep dive on this

15Saffron ExtractSaffron, 15 mg twice a dayEarly evidence

Saffron extract

For: Early research

A spice extract that raised erection scores in several trials.

What to do

  1. Take 15 mg of a standardized extract twice a day.
  2. Use a named, standardized extract. Saffron is often faked.
  3. Give it 4 weeks.
How much
30 mg a day
When
15 mg twice a day
How long
4 weeks

What happened in the studies

Score up 5.36 points

Across 3 pooled trials, saffron raised the erection score by 5.36 points against a dummy pill.

¹ Avicenna journal of phytomedicine, 2018. The study is under The science, below.

Watch out

Mild stomach or nervous-system effects. Never above the trial dose. On a blood thinner or with bipolar disorder: ask first.

The science
In detail
Early research: 30 mg a day of a standardized saffron extract, as 15 mg twice a day, the trial dose. Give it four weeks. A named standardized extract or nothing: saffron is often faked.
Found
Erection score up 5.36. Three trials pooled: saffron raised every part of the erection questionnaire, the erection score by 5.36 points. A 2026 review of 14 herbal trials: saffron improved erections.
Why
Crocin and crocetin, its active compounds, are antioxidants. They are thought to protect the nitric oxide signal that opens the arteries to the penis.
Watch
Mild stomach and nervous-system effects are the usual ones. High doses are toxic: stay at the trial dose. It may raise the bleeding tendency: ask first on a blood thinner. With bipolar disorder, ask a doctor first: it can lift mood or agitate. Rarely, an allergy. Products are often adulterated: a named standardized extract only.
The doses the studies used30 mg a day 15 mg twice a day, the four-week trial dose
30 mg a day

saffron (15 mg twice per day) PMID 22552758

The studies

saffron had a significantly positive effect on all dimensions of Erectile Function questionnaire (MD for Erectile function=5.36(p=0.00), Orgasmic function=1.12 (p=0.007), Overall satisfaction=1.23 (p=0.005), Satisfaction with intercourse=2.18 (p=0.00) and Sexual desire=0.78 (p=0.00), Fixed effects model using 3 trials).

PMID 29881706 · A systematic review and meta-analysis of clinical trials on saffron (Crocus sativus) effectiveness and safety on erectile dysfunction and semen parameters. · Avicenna journal of phytomedicine, 2018

The sentence around it

…Quantitative analysis showed that saffron had a significantly positive effect on all dimensions of Erectile Function questionnaire (MD for Erectile function=5.36(p=0.00), Orgasmic function=1.12 (p=0.007), Overall satisfaction=1.23 (p=0.005), Satisfaction with intercourse=2.18 (p=0.00) and Sexual desire=0.78 (p=0.00), Fixed effects model using 3 trials).

Saffron was effective in improving erectile function, orgasmic function, and intercourse satisfaction

PMID 41696741 · Herbal dietary supplements for erectile dysfunction: A systematic review and meta-analysis of randomized-controlled trials. · Journal of traditional and complementary medicine, 2026

The sentence around it

Saffron was effective in improving erectile function, orgasmic function, and intercourse satisfaction, while ginseng benefited erectile function, orgasmic function, sexual desire, overall satisfaction, and serum testosterone levels.…

The deep dive on this

16Tongkat AliTongkat ali, 300 mg a day, tested batchEarly evidence

Tongkat ali

For: Early research

A root extract that raised erection scores against a dummy pill.

What to do

  1. Take 300 mg of standardized water extract a day.
  2. Only a batch with a third-party test for heavy metals.
  3. Give it 12 weeks, then rescore.
How much
300 mg
When
Daily
How long
12 weeks

What happened in the studies

Erection scores up

In a 12-week trial with 109 men, erection scores rose more on tongkat ali than on a dummy pill.

¹ Evidence-based complementary and alternative medicine, 2012. The study is under The science, below.

Watch out

Often faked or spiked. In two market surveys, a quarter to a third of products carried mercury above the legal limit: choose a third-party tested product. It can disturb sleep. Rare liver injury. Hormone-sensitive condition: ask first. It is not authorized as a food in the EU, where a safety review raised a DNA-damage concern.

The science
In detail
Early research: 300 mg a day of a standardized water extract of the root, the trial dose, for 12 weeks. Only a batch with a third-party test for heavy metals.
Found
Erection score up in 12 weeks. A 12-week trial, 109 men: the erection score rose more on tongkat ali than on placebo, and libido rose 14%. A 6-month trial: 200 mg a day with training three times a week gave the biggest gain in erection scores.
Why
The root extract raises testosterone where it starts low, and testosterone helps keep the erection machinery working.
Watch
Product contamination and adulteration: this is the plant most often found spiked or substituted. In two market surveys of tongkat ali products, a quarter to a third carried mercury above the legal limit. Choose a product with a third-party test for heavy metals. Sleep trouble, restlessness and irritability for some; rare liver injury. With a hormone-sensitive condition, such as prostate cancer, ask a doctor first. In the EU it is not authorized as a food; a safety review there raised a DNA-damage concern.
The doses the studies used300 mg a day twelve weeks: erection score up against placebo
200 mg a day300 mg a day

300 mg of water extract of E. longifolia PMID 23243445

The studies

The EL group showed higher scores in the overall Erectile Function domain in IIEF (P < 0.001)

PMID 23243445 · Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men. · Evidence-based complementary and alternative medicine, 2012

The sentence around it

The EL group showed higher scores in the overall Erectile Function domain in IIEF (P < 0.001), sexual libido (14% by week 12), SFA- with sperm motility at 44.4%, and semen volume at 18.2% at the end of treatment.…

Erectile function demonstrated improvements in both interventions; however, the most significant results were obtained by men allocated to concurrent training + Eurycoma longifolia.

PMID 33541567 · A 6-month, double-blind, placebo-controlled, randomized trial to evaluate the effect of Eurycoma longifolia (Tongkat Ali) and concurrent training on erectile function and testosterone levels in androgen deficiency of aging males (ADAM). · Maturitas, 2021

The sentence around it

…Results Erectile function demonstrated improvements in both interventions; however, the most significant results were obtained by men allocated to concurrent training + Eurycoma longifolia.

The deep dive on this

With a doctor

Everything in this group is a decision for you and a doctor who has your history. It is here so you walk in knowing what to ask for.

17SildenafilThrough a doctor or pharmacist: 50 mg an hour beforeStrong evidence

Sildenafil

For: Erections, on the night

The first-choice pill. Take it about an hour before sex. It needs arousal to work.

What to do

  1. Get it through a doctor or a pharmacist.
  2. Start at 50 mg, about an hour before sex.
  3. Give it several tries. The doctor can move it to 25 or 100 mg.
How much
50 mg
When
An hour before sex
How long
Several tries

Standard practice

Prescription in the US; in the UK sildenafil is also sold by pharmacies. The US label: 50 mg about an hour before sex, anywhere from 30 minutes to 4 hours before. Up to 100 mg or down to 25 mg, once a day at most.

What happened in the studies

69%of attempts worked

In 2 trials with 861 men, 69% of attempts at sex worked on sildenafil, against 22% on a dummy pill.

¹ The New England journal of medicine, 1998. The study is under The science, below.

Watch out

Never with nitrate heart drugs, poppers or riociguat: blood pressure can crash and kill. Not if your heart is not fit for sex, or you are allergic to it. On an alpha-blocker, another blood-pressure drug, an HIV drug or some antibiotics and antifungals, or with liver or kidney disease: the doctor starts low. Never with another erection pill. Bleeding problems or a stomach ulcer: ask first. It does not protect against sexually transmitted infections. An erection over 4 hours: emergency. Sudden loss of sight or hearing: stop and get help. Once a day at most. Headache and flushing are common.

The science
In detail
The label start is 50 mg, about an hour before sex, on an empty stomach for a faster start. The doctor moves it to 25 or 100 mg. It needs arousal to work. Give it several tries before judging.
Found
69% of attempts worked, against 22%. Two trials, 861 men: 69% of attempts at sex succeeded on sildenafil, against 22% on placebo, and higher doses worked better. Sixteen head-to-head trials: tadalafil and sildenafil worked about the same.
Why
It blocks PDE5, the enzyme that switches the erection signal off. With arousal, nitric oxide opens the arteries to the penis, and the drug keeps them open longer.
Watch
Never with a nitrate or nitrite in any form, poppers included, or with riociguat: blood pressure can crash. Not if sex is unsafe for your heart. Not with a known allergy to it. On an alpha-blocker: be stable on it first, start at 25 mg. Other blood-pressure drugs: blood pressure can drop. Ritonavir: 25 mg at most in 48 hours; other strong enzyme blockers, such as some antifungals, or erythromycin: start at 25 mg. Liver or severe kidney disease: start at 25 mg. Not with another PDE5 drug or erection treatment. Bleeding disorders or an active stomach ulcer: safety unknown. No protection against sexually transmitted infections. An erection over 4 hours: emergency care. Sudden loss of vision or hearing: stop and get help. Once a day at most. Headache, flushing, indigestion, blurred or blue-tinged vision, stuffy nose.
The doses the studies used50 mg the label start for most men
25 mg50 mg100 mg

532 men were treated with oral sildenafil (25, 50, or 100 mg) or placebo PMID 9580646

The studies

In the last four weeks of treatment in the dose-escalation study, 69 percent of all attempts at sexual intercourse were successful for the men receiving sildenafil, as compared with 22 percent for those receiving placebo (P<0.001).

PMID 9580646 · Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group. · The New England journal of medicine, 1998

Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients' sexual confidence.

PMID 28741090 · Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis. · International urology and nephrology, 2017

The sentence around it

…Conclusion Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients' sexual confidence.

18TadalafilThrough a doctor: 10 mg on demand, or 2.5 to 5 mg dailyStrong evidence

Tadalafil

For: Erections, all weekend or daily

The long-lasting pill. One dose covers up to 36 hours, or a small daily dose means no timing.

What to do

  1. Ask a doctor: on demand or daily.
  2. On demand: start at 10 mg before sex.
  3. Daily: start at 2.5 mg, same time each day.
  4. Never with nitrate heart drugs.
How much
10 mg, or 2.5 to 5 mg daily
When
Before sex, or daily
How long
Months, taken daily

Standard practice

Prescription only. The US label: as needed, start at 10 mg before sex, up to 20 mg or down to 5 mg. Once a day at most; it works up to 36 hours. Daily, start at 2.5 mg, up to 5 mg.

What happened in the studies

Most effective of its kind

In 11 trials with 2,102 men, it improved erections in every group studied. Across 118 trials it ranked the most effective.

¹ The journal of sexual medicine, 2005. The study is under The science, below.

Watch out

Never with nitrate heart drugs, poppers or riociguat: blood pressure can crash and kill. Emergency nitrates wait 48 hours after a dose. Not if your heart is not fit for sex, or after a serious allergy to it. On an alpha-blocker, another blood-pressure drug or an HIV drug, with kidney or liver disease, or drinking heavily: blood pressure can drop, so the doctor lowers the dose. Never with another erection pill. Bleeding problems or a stomach ulcer: ask first. It does not protect against sexually transmitted infections. An erection over 4 hours: emergency. Sudden loss of sight or hearing: stop and get help. Headache, back ache and muscle ache are common.

The science
In detail
On demand, the label start is 10 mg before sex, moved to 5 or 20 mg; it works for up to 36 hours. Daily, the label start is 2.5 mg, raised to 5 mg, with no timing at all. Never with a nitrate.
Found
Most effective of its class, 118 trials. Eleven trials, 2,102 men: 10 and 20 mg improved erections in every group analyzed. Six trials, 1,596 men: 5 mg daily improved erections over six months or more. Across 118 trials it ranked the most effective of its class.
Why
It blocks PDE5, the enzyme that switches the erection signal off. It lasts much longer in the blood than sildenafil, which is why one dose covers a weekend, and a daily dose removes the timing.
Watch
Never with a nitrate in any form, or riociguat: blood pressure can crash. If a nitrate is needed in an emergency, at least 48 hours after the last dose, under close watch. Not if sex is unsafe for your heart. Not after a serious allergy to it. With an alpha-blocker: be stable on it first, start at the lowest dose. Other blood-pressure drugs, or 3 or more US standard drinks (5 or more UK units of alcohol): blood pressure can drop. Ritonavir or other strong enzyme blockers: 10 mg at most once every 72 hours, or 2.5 mg daily. Kidney or liver disease: lower limits. Not with another PDE5 drug or erection treatment. Bleeding disorders or an active stomach ulcer: only with caution. No protection against sexually transmitted infections. An erection over 4 hours: emergency care. Sudden loss of vision or hearing: stop and get help. Headache, indigestion, flushing, stuffy nose, and back or muscle ache 12 to 24 hours after.
The doses the studies used10 mg on demand the label start for as-needed use
5 mg daily10 mg on demand20 mg on demand

tadalafil 10 mg (N=321) PMID 16422847

The studies

Patients taking tadalafil 10 mg or 20 mg demonstrated significant improvement (P<0.005) from baseline to end point on the IIEF EF domain score in all subpopulations analyzed compared with patients receiving placebo.

PMID 16422847 · The efficacy of tadalafil in clinical populations. · The journal of sexual medicine, 2005

The sentence around it

…Results Patients taking tadalafil 10 mg or 20 mg demonstrated significant improvement (P<0.005) from baseline to end point on the IIEF EF domain score in all subpopulations analyzed compared with patients receiving placebo.

tadalafil seems to be the most effective agent, followed by vardenafil

PMID 23395275 · Comparative effectiveness and safety of oral phosphodiesterase type 5 inhibitors for erectile dysfunction: a systematic review and network meta-analysis. · European urology, 2013

The sentence around it

…Conclusions In recommended doses, oral PDE5-Is are more effective than placebo for ED, and tadalafil seems to be the most effective agent, followed by vardenafil.…

The deep dive on this

19Vacuum deviceA vacuum pump with a limiter, when pills fail or are ruled outModerate evidence

A vacuum erection device

For: When pills fail or are ruled out

A pump draws blood into the penis and a ring holds it. No drug needed.

What to do

  1. Ask a urologist or your doctor to show you.
  2. Use only a pump with a vacuum limiter.
  3. Place the ring at the base before sex.
How much
One device
When
Before sex
How long
As needed

Standard practice

The specialist guideline: offer vacuum devices, and only ones with a vacuum limiter. Patient and partner satisfaction is high. Vacuum pumps work for most men and suit those who cannot take the pills.

What happened in the studies

Works for most

In a review across many causes, the vacuum device worked, and side effects were short-lived.

¹ The journal of sexual medicine, 2013. The study is under The science, below.

Watch out

Only a pump with a limiter. Bruising or numbness can happen. On blood thinners: ask first.

The science
In detail
A tube over the penis and a pump draw blood in; a ring at the base holds it. Use one with a vacuum limiter only. A urologist or your doctor shows you how, and it works with the pills or without them.
Found
Works across the causes. A review of the device across many causes of erection problems: it worked across them, and the side effects were short-lived. The authors call it a strong second-line choice.
Why
It does not need the nerves or the nitric oxide signal. The vacuum pulls blood into the penis mechanically, and the ring stops it draining away.
Watch
Use only a device with a vacuum limiter: too much suction can injure the penis. Bruising and a cold or numb feeling can happen. Blood thinners or a bleeding disorder: ask the doctor first.

The study

The VED has continued to show efficacy for treatment of ED due to various etiologies and should be considered an attractive second-line therapy.

PMID 23347150 · The resurgence of the vacuum erection device (VED) for treatment of erectile dysfunction. · The journal of sexual medicine, 2013

The sentence around it

…Conclusions The VED has continued to show efficacy for treatment of ED due to various etiologies and should be considered an attractive second-line therapy.

Studies have demonstrated efficacy in ED associated with a variety of conditions.

The sentence around it

…Results Studies have demonstrated efficacy in ED associated with a variety of conditions.

20Alprostadil, when pills failWhen the pills fail: a urologist, and alprostadilStrong evidence

Alprostadil, when pills fail

For: When pills fail

A specialist drug that works straight on the erectile tissue, when the pills fail.

What to do

  1. When pills fail, ask for a urologist.
  2. The first dose is a test in the clinic.
  3. Use it no more than 3 times a week.
How much
Set in the clinic
When
Before sex
How long
Up to 3 times a week

Standard practice

Prescription only, through a specialist, with a first test dose in the clinic. The US label rules it out with conditions prone to a lasting erection, scarring or Peyronie’s disease, or an implant. No more than 3 times a week, at least 24 hours apart.

What happened in the studies

Worked after 94% of doses

In a 6-month study with 683 men, sex was possible after 94% of doses.

¹ The New England journal of medicine, 1996. The study is under The science, below.

Watch out

Not with sickle cell, myeloma or leukemia, scarring or Peyronie’s disease, or an implant. An erection over 4 hours is an emergency. Get the penis checked about every 3 months. At most 3 times a week, 24 hours apart. Never mixed with other drugs of its kind. The fine needle can break. Blood thinners: more bleeding. It does not protect against sexually transmitted or blood-borne infections. Pain at the site is common.

The science
In detail
A urologist’s option when the pills fail or are ruled out: a drug placed in the erectile tissue that works without the nerve signal. The first dose is a test in the clinic, and the clinic sets your dose.
Found
Sex possible after 94% of doses. A six-month home-use study, 683 men: sex was possible after 94% of doses, and men and partners rated it satisfying after 87% and 86%. Every dose beat placebo in a 296-man dose trial.
Why
It relaxes the smooth muscle of the erectile tissue directly, so it works even when the nerves or the nitric oxide step have failed.
Watch
Not with sickle cell disease or trait, multiple myeloma or leukemia, which raise the risk of a lasting erection. Not with scarring of the penis, Peyronie’s disease, or an implant. An erection over 4 hours: emergency care. Scarring of the penis can develop: regular checks, about every 3 months. No more than 3 times a week, 24 hours apart. Not with other drugs of its kind in the penis. The fine needle can break. Blood thinners: more bleeding. It gives no protection from sexually transmitted or blood-borne infections, and the small bleed can pass them on. Pain at the site is common.

The study

In a six-month self-injection study in 683 men, the participants reported being able to have sexual activity after 94 percent of the injections.

PMID 8596569 · Efficacy and safety of intracavernosal alprostadil in men with erectile dysfunction. The Alprostadil Study Group. · The New England journal of medicine, 1996

The men and their partners rated the sexual activity as satisfactory after 87 and 86 percent of the injections, respectively.

The deep dive on this

21Penile implantWhen nothing else works: an implant, through a urologistStrong evidence

Penile implant

For: When nothing else works

A device fitted inside the penis. An erection whenever you want it.

What to do

  1. When pills, pumps and alprostadil have failed, ask a urologist.
  2. Talk through the inflatable and bendable types.
  3. Know it is permanent.
How much
One operation
When
Last line
How long
Permanent

Standard practice

The specialist guideline: tell men about implants, including their benefits and burdens. It is best seen as irreversible, and is not done with an infection present.

What happened in the studies

83%satisfied

Across 83 studies with 12,132 men, 83% were satisfied with their implant.

¹ Andrology, 2025. The study is under The science, below.

Watch out

Surgery risks, infection most of all. It is permanent.

The science
In detail
When nothing else works: a urologist fits an implant inside the penis. The inflatable kind fills from a small pump in the scrotum; there is a bendable kind too. It gives an erection on demand, for as long as you want.
Found
Eighty-three studies, 12,132 men: 83% were satisfied with their implant, and satisfaction grew over time. Long-term complications ran from 3% to 4.6%.
Why
It replaces the job of the erectile tissue with a device, so it works whatever the cause.
Watch
Surgery risks, and infection above all: never fitted with an active infection. It is best seen as permanent: other treatments are unlikely to work after removal. Devices can fail and may need replacing.

The study

Overall, a high patient satisfaction rate was observed 83[80; 86]%.

PMID 39010798 · Long-term penile prosthesis couple's satisfaction: A systematic review and meta-analysis. · Andrology, 2025

Patient and partner satisfaction is excellent and increases with time.

The sentence around it

…Conclusions Patient and partner satisfaction is excellent and increases with time.

22Testosterone therapy, if the morning test is lowTestosterone therapy, only when the morning tests are lowModerate evidence

Testosterone therapy, if the morning test is low

For: Low testosterone, confirmed

Testosterone from a doctor, only when tests confirm it is low. Fixing the level can help the erections and the pills.

What to do

  1. Only after two low morning tests and the symptoms.
  2. Trying for a child? Say so first: it stops sperm production.
  3. Your doctor sets the dose and checks the blood count and the prostate.
  4. Leg pain and swelling, or sudden breathlessness: stop and get seen.
How much
Doctor-set
When
As prescribed
How long
Ongoing

Standard practice

On the gel, blood pressure is measured periodically, and children keep off the skin where it went on.

What happened in the studies

Sexual function up

In 17 trials, where testosterone was low, treatment improved sexual function against a dummy treatment.

¹ The lancet. Healthy longevity, 2023. The study is under The science, below.

Watch out

It can suppress sperm production. Blood pressure, red blood cells and the risk of blood clots can rise. It is ruled out by breast or prostate cancer, and the prostate is checked. It can worsen sleep apnea, cause swelling and grow breast tissue. It is not established for low testosterone that comes with age. In the biggest safety trial, an irregular heartbeat, kidney injury and lung clots were more common on it. Boxed warning on the gel: children and women must not touch the skin where it went on; cover it and wash your hands. It can be abused and can cause dependence.

The science
In detail
Only when repeat morning tests confirm low testosterone, with the symptoms. A doctor prescribes it and sets the dose on your blood tests. A pill may work better with it added. It shuts down sperm production, so trying for a child comes first. The full detail: TRT. UK and US: prescription only.
Found
Sexual function up 5.52 points. Pooled data from 17 trials: where testosterone was low, treatment raised the full sexual function score by 5.52 points against placebo, and the erection subscore rose with it. The biggest safety trial dosed a daily 1.62% gel to 350 to 750 ng/dL.
Why
Testosterone drives desire and helps keep the erection machinery working. When it is truly low, putting it back gives a pill more to work with.
Watch
The label: sperm production can be suppressed. Red cell count and blood pressure can rise, and blood clots in the legs and lungs have been reported. The prostate is checked before and during treatment, and breast or prostate cancer rules it out. It can worsen sleep apnea, cause fluid retention and grow breast tissue. Its safety and benefit in age-related low testosterone are not established. On the gel, children and women must not touch the skin where it went on. In the biggest safety trial, atrial fibrillation, kidney injury and clots in the lung were more common on testosterone. It has been abused at high doses, with serious heart and mental-health harms, and the label lists dependence.
The doses the studies used1.62% gel, to 350 to 750 ng/dL the safety trial's dose, adjusted on the blood tests
1.62% gel, to 350 to 750 ng/dL

daily transdermal 1.62% testosterone gel (dose adjusted to maintain testosterone levels between 350 and 750 ng per deciliter) PMID 37326322

The study

Compared with placebo, testosterone treatment increased 15-item International Index of Erectile Function (IIEF-15) total score (mean difference 5·52 [95% CI 3·95-7·10]

PMID 37804846 · Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis. · The lancet. Healthy longevity, 2023

The sentence around it

Compared with placebo, testosterone treatment increased 15-item International Index of Erectile Function (IIEF-15) total score (mean difference 5·52 [95% CI 3·95-7·10]; τ 2 =1·17; n=1412) and IIEF-15 erectile function subscore (2·14 [1·40-2·89]; τ 2 =0·64; n=1436), reaching the minimal clinically important difference for mild erectile dysfunction.…

The deep dive on this

23Weight loss with a GLP-1 medicineA GLP-1 medicine, if you carry extra fatEarly evidence

Weight loss with a GLP-1 medicine, if you carry extra fat

For: Carrying a lot of extra fat

A weekly shot from a doctor that turns hunger down, for a man with a lot of fat to lose. Erection scores rose as the weight came off.

What to do

  1. Only if you carry a lot of extra fat, on a prescription.
  2. Start at 0.25 mg a week; step up every 4 weeks.
  3. Keep lifting and keep the protein high.
  4. Rescore at 3 months.
How much
0.25 mg to 2.4 mg a week
When
Once a week
How long
Long term

Standard practice

Semaglutide starts at 0.25 mg once a week and steps up every 4 weeks to 1.7 or 2.4 mg. A step not tolerated waits 4 weeks. Heart rate is checked at regular intervals. Prescription only, in the UK and the US.

What happened in the studies

Erection score up

In seven pooled studies, the erection score rose on a GLP-1 medicine.

¹ World journal of methodology, 2026. The study is under The science, below.

Watch out

Boxed warning: thyroid tumors in rodents. Never with a personal or family history of medullary thyroid cancer or MEN 2, or after a serious allergy to it. A neck lump, trouble swallowing or a hoarse voice that lasts: tell the doctor. The dose climbs every 4 weeks. Severe belly pain that will not go, maybe into the back, can be pancreatitis: stop and get seen. Gallstones, low sugar with insulin or other diabetes pills, kidney injury if sickness dries you out, and severe gut side effects. Allergic swelling of the face or throat: emergency. Diabetic eye disease can worsen. Your resting heart rate rises: report a racing heart at rest. Tell anyone sedating you. The tablet can raise levothyroxine levels. Never share a pen. Sudden vision loss in one eye: urgent help. Some men report erection trouble on these drugs: tell the doctor. Keep lifting and keep the protein up, or muscle goes with the fat.

The science
In detail
If you carry a lot of extra fat, a GLP-1 medicine through a doctor takes it off faster than food alone, and erection scores rose with it. It is prescribed for obesity, or overweight with a weight-related condition. The usual start is semaglutide 0.25 mg a week, stepping up every 4 weeks to 2.4 mg. Keep lifting and keep the protein up. The other options and the full plan: Weight loss injections and surgery.
Found
Erection score up 2.73 points. Seven studies pooled: on a GLP-1 medicine, the erection score rose 2.73 points, and total testosterone rose with it.
Why
Belly fat damages the lining of the small arteries the erection depends on, and turns testosterone into estrogen. Taking the fat off works on both.
Watch
The label's boxed warning: thyroid C-cell tumors in rodents. So never with a personal or family history of medullary thyroid cancer or MEN 2. A lump in the neck, trouble swallowing, breathlessness or a hoarse voice that lasts: tell the doctor. Never after a serious allergic reaction to it. The dose steps up every 4 weeks. If a step is not tolerated, the next is delayed 4 weeks. Severe gut side effects, and not with severe gastroparesis. Pancreatitis: severe belly pain that will not go, sometimes into the back, means stop it and get seen. Gallstones and gallbladder inflammation. Low blood sugar with insulin or a sulfonylurea. Kidney injury when sickness or diarrhea dries you out. Anaphylaxis and swelling of the face or throat. Diabetic eye disease can get worse. The resting heart rate rises and is checked at regular intervals. A racing heart at rest: tell the doctor. Food can stay in the stomach under anesthesia or deep sedation: tell the team before any procedure. The tablet form raised levothyroxine levels 33%. Never share a pen. A sudden loss of vision, usually in one eye: urgent help. Some men report erection trouble on these medicines: tell the doctor if it gets worse. Muscle goes with the fat unless you keep lifting and keep the protein high.

The study

GLP-1 agonist therapy improved ED score with a significant statistical difference, MD = 2.73, 95% confidence interval (CI): 1.64-3.83.

PMID 42626264 · Glucagon-like receptor-1 agonists and impotence: A meta-analysis. · World journal of methodology, 2026

A significant increase was found regarding TT, SHBG, and FSH, MD 73.04, 95%CI: 16.91-129.17, MD 7.00, 95%CI: 1.71-12.30, and MD 0.46, 95%CI: 0.01-0.91 respectively.

How you'll know it's working

Track
Your IIEF-5 erection score, 5 to 25
How to track
Answer the five questions before you start, then once a month. Same questions, same honest answers. Note what changed that month.
When to judge
A pill works on the night. Training, weight and quitting smoking take months: the pelvic floor trial judged at three months, the smoking studies at six. Judge the lifestyle work at three months against your first score.

Why this happens

You get hard, then lose it. Or it will not come at all with your partner, though it works fine on your own. The next time you are already worrying before you start, and the worry makes it worse.

The pipes

An erection is blood flow. Arousal releases nitric oxide, the arteries open, and the erectile tissue fills. The arteries of the penis are narrow, so damage to the vessel lining shows up there before the heart.

The alarm

Adrenaline shuts the erection down. Fear of failing, watching yourself mid-sex, and stress all fire it. That is why it can work alone and fail with a partner.

The switch

The enzyme PDE5 switches the erection signal off. The pills block it, so the signal lasts. They need arousal and working arteries to have something to hold on to.

Hard cardioWeight down, smokingstoppedHeart numbers treatedSmoking, belly fat, highsugarBetter blood flowSensate focus at homeThe pattern checkedMood and sleep treatedFear of failingArousal that buildsSildenafilTadalafilPelvic floor holding itNitrates rule the pillsoutAn erection that lastsFirm,reliableerectionswith yourpartnerFirm,reliableerectionswith yourpartnerFirm,reliableerectionswith yourpartnerFirm,reliableerectionswith yourpartnerThe pipesThe alarmThe switchHard cardioWeight down, smoking stoppedHeart numbers treatedSmoking, belly fat, high sugarBetter blood flowSensate focus at homeThe pattern checkedMood and sleep treatedFear of failingArousal that buildsSildenafilTadalafilPelvic floor holding itNitrates rule the pills outAn erection that lastsFirm, reliable erectionswith your partnerFirm, reliable erectionswith your partnerFirm, reliable erectionswith your partnerFirm, reliable erectionswith your partnerThe pipesThe alarmThe switch
Figure 2. How the moves lead to firm, reliable erections with your partner. The dotted orange boxes are the things to cut back.

Week by week

Why this order

The checks come first because a weak erection can be the first sign of heart trouble. Training, weight and quitting smoking fix the blood supply underneath. The pills go on top, and the devices stay with a urologist.

0123456789101112Weeks from the startScore, heart check, THard cardioPelvic floorWeight, smoking, dietA pill, if you want oneSensate focus, if nervesThe reviewReview, week 12024681012Weeks from the startScore, heart check, THard cardioPelvic floorWeight, smoking, dietA pill, if you want oneSensate focus, if nervesThe reviewReview, week 12
Figure 3. The plan by week: navy bars keep going, orange bars are the moves you add, white bars are checks and decisions. The starburst marks the review at week 12.
WhenAddWhy then
Week 0Take the five-question score. Book blood pressure, lipids, blood sugar and a morning testosterone test. List every medicine. Chest pain on effort: a doctor before anything else.A weak erection can be the first sign of heart trouble. The checks come before the pills.
Week 0, the patternNotice morning and solo erections for a week. Low mood or loud snoring: your doctor.It tells you whether to start with the head route or the blood supply.
Weeks 1 to 12, the foundationForty minutes of hard cardio four times a week. Pelvic floor squeezes three times a day. Quit smoking, lose weight if you carry extra, eat Mediterranean, drink under 8 US standard drinks (14 UK units).These fix the blood supply the pills depend on.
Any week, the pillSildenafil 50 mg an hour before, or tadalafil 10 mg on demand or 2.5 mg daily, through a doctor. Never with nitrates.A pill works on the night while the foundation builds.
Any week, if it is nervesSensate focus at home as a couple, or a structured online self-help program. A pill alongside is fine.Touch with no goal takes the pressure off, and the gain grew over 6 months.
Week 12Retake the score and compare it with the first. Pills not enough: a urologist for a vacuum device, alprostadil, or an implant.The number tells you what is working and when to step up.

What to track

One number: your five-question erection score, 5 to 25, before you start and once a month. Read the run of scores, not one bad night.

The log is short: the score, morning erections that week, cardio sessions, pelvic floor sets, and any pill and dose. If it works alone but not with a partner, note it.

The erection log

DayIIEF-5 scoreMorning erections this weekCardio sessionsPelvic floor setsPill and dose, if any
Mon     
Tue     
Wed     
Thu     
Fri     
Sat     
Sun     
  • IIEF-5 score, once a month: it should climb. 22 or more is the normal zone.
  • Blood pressure, lipids and HbA1c from the heart check, then as your doctor sets.
  • Morning total testosterone, once, repeated if low.
  • Morning erections: a sign the blood supply works.
  • Lines that take a man to a doctor now: chest pain, an erection over 4 hours, or erection loss with back pain or numbness.

Doses at a glance

The amounts the studies used, move by move. The label or your doctor sets your dose.

MoveWhat the studies usedWhenHow longStudy
1. Get fit: hard cardio, four times a week40 minutes, moderate to hard4 times a week6 monthsPMID 27707739
2. Lose weight, if you carry extraLose 10% or moreWeigh weeklyThe trial ran 2 yearsPMID 15213209
3. Stop smoking and vaping nicotineStop completelyNowRescore at 6 monthsPMID 21883852
4. Eat MediterraneanMost mealsDailyThe trial ran 2 yearsPMID 16395320
5. Treat the heart numbers, cut the drinkTreat what the check findsUnder 8 US standard drinks (14 UK units) a weekRescore at 3 monthsPMID 21911624
6. Train the pelvic floorSqueeze, hold, release3 times a day3 monthsPMID 15527607
7. The home program: sensate focus, as a coupleA few sessions a weekAt home, as a coupleAbout 7 weeksPMID 41926207
8. Shockwave therapyA course of sessionsOver weeksInvestigationalPMID 41906634
9. Red ginseng900 mg, three times a dayBefore the afternoon8 weeksPMID 18754850
10. Arginine1.5 to 5 g a dayDailyJudge at 4 to 8 weeksPMID 30770070
11. Citrulline1.5 g a dayDailyA monthPMID 21195829
12. French maritime pine bark, with arginine1.7 g arginine, plus 80 to 120 mg barkDaily, split through the day2 to 3 monthsPMID 37908749
13. Tribulus1,500 mg a day, as two 250 mg tablets three timesAfter meals12 weeksPMID 40360723
14. Maca root2,400 mg dry extract a dayDaily, in the morning12 weeksPMID 19260845
15. Saffron extract30 mg standardized extract15 mg twice a day4 weeksPMID 29881706
16. Tongkat ali300 mg standardized water extractDaily12 weeksPMID 23243445
17. Sildenafil50 mg to start; 25 to 100 mgAbout an hour before sexSeveral tries before judgingPMID 9580646
18. Tadalafil10 mg on demand; 2.5 to 5 mg dailyOn demand, before sex; daily, any hour6 months or more in the daily trialsPMID 16422847
19. A vacuum erection deviceOne device, with a limiterBefore sexWhen pills are not enough, or not allowedPMID 23347150
20. Alprostadil, when pills failSet in the clinicBefore sexAt most 3 times a weekPMID 8596569
21. Penile implantOne operationWhen other options have failedPermanentPMID 39010798
22. Testosterone therapy, if the morning test is lowDoctor-set, on the blood testsDaily, as prescribedOngoingPMID 37804846
23. Weight loss with a GLP-1 medicine, if you carry extra fatSemaglutide 0.25 mg a week to start; 2.4 mg to keepOnce a weekSteps every 4 weeks; rescore at 3 monthsPMID 42626264

Deep dives

The studies

Every study behind this page, newest first.

Words on this page

Standardized mean difference (SMD)
A way to put results measured on different scales onto one scale. About 0.2 is a small effect, 0.5 medium and 0.8 large.
95% CI
The range the true result probably sits in. The narrower the range, the surer the result.
Meta-analysis
Many studies pooled into one result.
RCT
A randomized controlled trial: people put by chance on the treatment or on a dummy version.
PMID
A study's ID number in PubMed, the public index of medical research.
Strong, moderate and early evidence
Strong: many human trials agree. Moderate: human studies point the same way. Early: the first small human studies.
Erectile dysfunction
Not being able to get or keep an erection firm enough for sex.
IIEF-5
A five-question erection score, 5 to 25. 21 or less points to a problem.
PDE5 inhibitor
The erection pill class: sildenafil and tadalafil. They block the enzyme that ends an erection.
Nitrates
Heart drugs for chest pain, and poppers. Deadly with the erection pills.
Priapism
An erection that will not go down. Over 4 hours is an emergency.
Performance anxiety
Fear of failing in bed that sets off the stress response and blocks the erection.
Pelvic floor
The muscles under the pelvis that stop the flow of pee and squeeze the base of the penis.
Alprostadil
A drug placed in the penis by a specialist route that works without the nerve signal.
Vacuum device
A tube and pump that draw blood into the penis, with a ring to hold it.
Investigational
Still being tested in trials and not yet a standard treatment.
Nitric oxide
The gas messenger that relaxes the artery walls in the penis so blood can flow in. The pills protect its signal.

Take the score tonight and book the heart check this week. The training and the pelvic floor do the long work, a pill handles the night, and the score tells you what is working.

When to see a doctor
  • Sudden chest pain that does not go away, or spreads to the arm, neck or jaw: call 911.
  • An erection lasting more than 3 to 4 hours: get emergency care. Do not drive yourself.
  • Back pain with loss of erections, numbness around the genitals, or new trouble peeing, or erection loss after a serious accident: call 911 or go to the ER.
  • Chest pain or breathlessness on effort with the erection trouble: see a doctor before any sex pill. Erection problems can come before heart disease.
  • Erection problems since a pelvic injury, or all your life: ask for a specialist. A young man with one blocked artery in the pelvis may be offered artery surgery.
  • A new bend in the penis when erect, a hard lump, or painful erections: see your doctor.
  • Erection problems that keep happening: see your doctor or a sexual health clinic.

I am not a doctor. This is not medical advice. This is self-education. Every dose on this page is the one a trial or a label used, quoted from it. It is not a prescription. Talk to a physician who has your history before anything in the With a doctor group.