Vitality

Fasting-induced autophagy

Fast because it makes you eat less. Not for the autophagy.

Vitality · Supplement · members

Intravenous NAD+

Skip the NAD+ drip. You'd pay four figures to cramp and vomit in a chair.

Vitality · Supplement · members

Metformin & the TAME trial

Skip metformin unless you're diabetic. It blunts what your training just built.

Vitality · Supplement · members

Everolimus

Don't pay for a rapalog. The one thing it's moved in people is a flu jab.

Vitality · Supplement · members

Disease-risk polygenic scores

Don't buy the DNA risk score. Your blood pressure tells you more.

Vitality · Device · members

Test-retest reliability of commercial epigenetic age tests

Don't buy a biological age test to score your protocol.

Vitality · Device · members

DunedinPACE

Don't buy the aging test. The one thing that moved it was eating less.

Vitality · Procedure · members

Second-generation epigenetic clocks

Skip the biological age test. Two years of eating less didn't shift the number.

Vitality · Procedure · members

First-generation epigenetic clocks

Don't build a protocol around your epigenetic age. It's guessing your birthday.

Vitality · Procedure · members

MTHFR C677T / A1298C genotyping

Ignore the MTHFR line on your DNA report, and skip the methylfolate.

Vitality · Procedure · members

Direct-to-consumer genotyping array

Spit in the tube if you like. Never act on the raw file without a lab test.

Vitality · Procedure · members

EMOM

Program the work first. Put it on the minute only to stop yourself dawdling.

Vitality · Practice · members