The libraryCalm

Microdosing Ketamine

The results that hold up are in depression that hadn't shifted on anything else, at a dose a doctor set.

Also called Low-Dose Ketamine, Very-Low-Dose Ketamine, Sublingual Ketamine, Oral Ketamine, Ketamine Troches, Ketamine Lozenges

Who it's forAny man mailed sublingual ketamine troches by a telehealth subscription.

The item

Three squares: proven in human trials. Two: a strong signal. One: early human data. Striped: the trials disagree.

Calm Willpower Recovery Focus

Buffs

Rapid reduction of depressive symptoms contested
Sustained mood benefit from repeated low-dose oral or sublingual…
Reduction in suicidal ideation
Reduction of post-traumatic stress symptoms contested
Anxiety reduction
Chronic pain relief & opioid sparing contested
Reduction in harmful alcohol consumption
Improved sleep depth & continuity
Enhanced neuroplasticity window
Preserved or improved cognition at therapeutic exposure contested

Debuffs

Know firstDissociation & perceptual disturbance
Know firstTransient increase in blood pressure & heart rate
Know firstNausea, vomiting, dizziness & sedation
Know firstMisuse, tolerance & dependence potential
ManageableKetamine-associated uropathy
ManageableCognitive impairment with frequent or high-dose use
ManageableHepatobiliary injury & liver enzyme elevation
ManageableHazards specific to unsupervised at-home administration
MildTachyphylaxis & diminishing response
MildPrecipitation of mania, psychosis or persistent perceptual disturbance
MildDisrupted sleep & next-day activation
MildRaised intraocular & intracranial pressure

“Use ketamine to break a depression, not to sharpen yourself up every day.”

Emergency: call 911.

I am not a doctor. This is not medical advice. This is self-education. Talk to a physician who has your history before you change anything.